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Science is a systematic enterprise that builds and organizes knowledge in the form of testable explanations and predictions about the universe. In an older and closely related meaning, "science" also refers to a body of knowledge itself, of the type that can be rationally explained and reliably applied. A practitioner of science is known as a scientist.

In modern usage, "science" most often refers to a way of pursuing knowledge, not only the knowledge itself. It is also often restricted to those branches of study that seek to explain the phenomena of the material universe. In the 17th and 18th centuries scientists increasingly sought to formulate knowledge in terms of laws of nature such as Newton's laws of motion. And over the course of the 19th century, the word "science" became increasingly associated with the scientific method itself, as a disciplined way to study the natural world, including physics, chemistry, geology and biology. It is in the 19th century also that the term scientist was created by the naturalist-theologian William Whewell to distinguish those who sought knowledge on nature from those who sought other types of knowledge.